Tablets are manufactured by
compressing a formulation having a drug or drugs with excipients on stamping
machine which are called tablet press or tablet compression machine. The
machine is a critical element of producing oral solid dosage formulations. To
form a tablet, a formulation having a drug is evaluated into a cavity created
by punches and dies. After this, punches are pressed together with great pressure
to fuse the matter together. In tabletcompression punches and dies system dies are used to give specific shape
and size to the tablet and punches are used to compress the material such as
drugs and drugs with excipients or granules within the dies.
For tablet pressing, controlling the
individual weight of tablets is critical. Two important factors which are
difficult to control, but are essential for tablet’s bioavailability (the rate and
degree at which a drug or a substance is absorbed into a living system) and
clinical effect, are disintegration rate and tensile strength. Conventional
tablet presses determine a tablet’s weight either by evaluating its variation
in tablet height at pre-compression or the pressure at main compression. These procedures,
however, pass over one major characteristic which is tensile strength. A
tablet’s tensile strength controls drugs bioavailability and clinical effect,
which are critical for any dosage form.
Punches and dies sets are available
in different types such as Regular shape punch die set, irregular shapes punch
die set, core rod tooling punch and die set, sealed groove punch and die set.
Regular shape punch and die set consists of round, capsule, oval and geometric
shapes. Usually, round shapes punch die sets are most commonly used by
pharmaceutical and veterinary sector. These punch die sets are offered in
different concavity, size and flat in plain or imprinted break line. Capsule
punch die set aids you to form tablets of capsule shape. These types of sets
are highly used in pharma and ayurvedic industries.
