Pharmaceutical tablet compression punches and dies

Tablets are manufactured by compressing a formulation having a drug or drugs with excipients on stamping machine which are called tablet press or tablet compression machine. The machine is a critical element of producing oral solid dosage formulations. To form a tablet, a formulation having a drug is evaluated into a cavity created by punches and dies. After this, punches are pressed together with great pressure to fuse the matter together. In tabletcompression punches and dies system dies are used to give specific shape and size to the tablet and punches are used to compress the material such as drugs and drugs with excipients or granules within the dies. 

For tablet pressing, controlling the individual weight of tablets is critical. Two important factors which are difficult to control, but are essential for tablet’s bioavailability (the rate and degree at which a drug or a substance is absorbed into a living system) and clinical effect, are disintegration rate and tensile strength. Conventional tablet presses determine a tablet’s weight either by evaluating its variation in tablet height at pre-compression or the pressure at main compression. These procedures, however, pass over one major characteristic which is tensile strength. A tablet’s tensile strength controls drugs bioavailability and clinical effect, which are critical for any dosage form.

Punches and dies sets are available in different types such as Regular shape punch die set, irregular shapes punch die set, core rod tooling punch and die set, sealed groove punch and die set. Regular shape punch and die set consists of round, capsule, oval and geometric shapes. Usually, round shapes punch die sets are most commonly used by pharmaceutical and veterinary sector. These punch die sets are offered in different concavity, size and flat in plain or imprinted break line. Capsule punch die set aids you to form tablets of capsule shape. These types of sets are highly used in pharma and ayurvedic industries.

Oval shape punch die sets aids you to form oval or ellipse shape tablets. Usually oval shape punch die sets are used in ayurvedic as well as pharma industries. Geometric shape punch die sets are enable you to form tablets with different geometric shapes such as rectangular, square, triangular, rohmbus benzene etc. These punch die sets are highly applicable in the industries such as pharmaceutical, chemical, confectionery, industrial powder metallurgy etc. Irregular shape punch die sets are used to form tablets in different shapes such as animals, fruits, vehicle, part of human body, etc. These punch die sets find its applications in confectionery industries.

Things you need to know before buying food and pharma machineries

There are several types of machines used in food and pharma industries for different applications such as filling, packaging, capping, sealing, labeling etc. Before buying these machines, it is important to know your requirement. For instance if you are buying a filling machine, you should determine the size of the container first because the machine to fill a bottle or vials will be completely different from the machines used to fill beverages in drums and big containers.

The filling equipment industry is driven by the advanced filling technology development and rising demand for the food packaging. The market for filling machines is classified as solid, semisolid, and liquid based on the different types of products. Leading food and pharma machineries exporter a offer a outstanding range of machines and equipments which are designed to fit needs in liquid filling & packaging in food and Pharma industries.

There are machines which suit your filling requirements from filling liquids into bags, pouches, vials, and jars to huge scale, high viscosity liquid filling in large containers. Liquid filling machineries that can efficiently handle foaming products are also available in the market. Top food and pharma machineries exporters assure a high degree of accuracy with their filling systems, but discovering which type of liquid a firm needs to fill can help in finding the right filling machine.

Before you start shopping and comparing machinery, answering a few important questions will aid you much when it comes to making a buying decision.

Performance of Automatic Ointment Manufacturing Plant

Ointment manufacturing plant is an ideal tool in the pharmaceutical and cosmetic sectors. In the production and handling of ointment, cream, lotions, tooth paste, gels etc. the manufacturing plant plays a significant role. It is specifically fabricated by using high-quality stainless steel and other metals by bearing two important factors in mind which have a major impact on volume of the ointment. One factor is that less man power is required for handling of ointment and other is that while mixing and blending vacuum drop is small.

Automatic Ointment Manufacturing Plant Includes The Following Parts:

• Manufacturing Vessel
• Water Melting Vessel
• Wax Heating Vessel
• Interlinked Pipeline
• Storage Vessel
• Working Platform
• Incorporated Automatic Control Panel.
• Vacuum Pump, Metering Pump and Bump Pump 

Some Specific Features Of Automatic Ointment Manufacturing Plant Are Mentioned Below:

• These manufacturing plants are easily used for loading and unloading of the semi-solid products.
• The installation of these plants is easy and cleaning is also done effortlessly.
• This manufacturing plant is compatible for dry mixing of products (powder form).
• All parts of this plant are fabricated by making the use of high-quality material, so the manufacturing plant is highly durable.
• These plants can be customized easily as per client’s requirement.
• These plants require minimum maintenance and are very cost effective.
• Automatic rotating facility which reduces the manpower and saves lot of money.
• These plants deliver high-quality end product in small time period.
• These plants are cost-effective, yet manufactured by using advanced technology. 

Maximize Performance!

This Automatic ointment manufacturing plant enhances the functionality and performance of your ointment manufacturing business and enables you to consistently maintain high levels of achievement. Highly advanced technology and state-of-art machinery is used in manufacturing and installing these ointment manufacturing plants.

Advent of New Segment - Pharma and Food Processing Machines Exporters

India as an underdog never had an edge of first-mover, particularly in bio-technological and mechanical arena. But with the aid of tie ups and mergers with olfactory multinationals, Indian Pharmaceutical Companies are benefited with the advanced R&D facilities and innovations. Technology is being taken to the new dimension of automation wherein human efforts are only directed and focused on strategically developing the series of activities like distribution system, marketing, and selling. After lot of innovations and research, professionals have come up with the automated machines in the pharma sector. And thus, India has evolved as a key player in exporting sophisticated food and pharma processing machines.  To name some, machines like Sheer mixture can mix  different powders uniformly or in the pre-described ratio an pellet machine is accoutred with function of rotatable matrix, adjustable pressing rollers etc. These machines are generic in nature and its functionality has been tested across the variety of product and climatic conditions.

These exporters handle the distribution of machines, from the production facility to the door of the buyer. This exporting industry will bridge the gap between demand and supply which is apparent in untapped market of underdeveloped Asian and Middle East countries. India should invest more in R&D and infrastructure doing away with its deficiency to come up with advanced machines and manufacture such machines domestically.

Bio-technology has lot of potential and opportunities to discover, exploit, and capitalize.  India is gradually moving from the service provider country to the end-to-end solution provider and this sector will nudge the pharmaceutical industry standing at 4th rank to higher rank.

Liquid Manufacturing Machine Exports a finished Product with Each Delivery

A liquid manufacturing machine has become one of the most crucial factors to be considered while making any liquid product. This is due to the simplicity that comes along with a liquid manufacturing plant for production of a liquid product. The importance has so much increased that this machine has become a part of GMP list as a prerequisite. This has also led to a surge in demand of liquid manufacturing machine exporters in order to gain the best machine and thereby the best product in the market.

The key to a finished liquid product is introduction of preservatives – a system that prevents microbial growth, failing which the liquid may not remain in its liquid form upon getting on the market shelf. This can be a huge disaster to the company if the consumers are faced with a promised liquid but get a solidified content; the company’s reputation is at stake then. A challenge in this field is that the liquid needs to be stable and ought to have the ingredients that are printed on the label till the expiry date.  This condition apart from other regulations involved in the part of material sourcing, bottling and packaging add to the complexities involved in liquid manufacturing process.

The formulation procedure is also a lengthy process that takes into account the ingredients required, basis of liquid, preservatives needed and the flavour to introduce in the solution. Not only the formulation procedure, but also the dosage form has to be kept in mind; for instance, a tablespoon of syrup may not be fit as one ml dose. Flavouring is another task that has to be dealt with precision as flavour has to be chosen as per the target group often. A formulation made for the kids may have to be sweeter than those made for the adults. A major impact that is responsible, as we may say, for the integrity of the formulation to stay in its liquid form and preserve the content of the solution.

PH of the formulation has to be kept in mind while formulating a compound as per the general pH requirement of the body of patients as well as that needed for maintaining preservatives in the compound. Preservatives used in the syrup can be many such as methyl parabens, propyl parabens, calcium sorbate, potassium sorbate, all benzoates and other such preservatives that work only in low pH. All of this requirement may be well achieved by certain companies that comply with GMP regulations. Even if there is a dearth of such a company, one may rely on a popular liquid manufacturing machine exporter that.

Liquid Manufacturing Machine Exports a finished Product with Each Delivery

The author is a researcher at a pharmaceutical equipment plant that specialises in, and is an exporter of, liquid manufacturing machines.

A liquid manufacturing machine has become one of the most crucial factors to be considered while making any liquid product. This is due to the simplicity that comes along with a liquid manufacturing plant for production of a liquid product. The importance has so much increased that this machine has become a part of GMP list as a prerequisite. This has also led to a surge in demand of liquid manufacturing machine exporters in order to gain the best machine and thereby the best product in the market.

The key to a finished liquid product is introduction of preservatives – a system that prevents microbial growth, failing which the liquid may not remain in its liquid form upon getting on the market shelf. This can be a huge disaster to the company if the consumers are faced with a promised liquid but get a solidified content; the company’s reputation is at stake then. A challenge in this field is that the liquid needs to be stable and ought to have the ingredients that are printed on the label till the expiry date.  This condition apart from other regulations involved in the part of material sourcing, bottling and packaging add to the complexities involved in liquid manufacturing process.

The formulation procedure is also a lengthy process that takes into account the ingredients required, basis of liquid, preservatives needed and the flavour to introduce in the solution. Not only the formulation procedure, but also the dosage form has to be kept in mind; for instance, a tablespoon of syrup may not be fit as one ml dose. Flavouring is another task that has to be dealt with precision as flavour has to be chosen as per the target group often. A formulation made for the kids may have to be sweeter than those made for the adults. A major impact that is responsible, as we may say, for the integrity of the formulation to stay in its liquid form and preserve the content of the solution.

This has also led to a surge in demand of liquid manufacturing machine exporters in order to gain the best machine and thereby the best product in the market.

pH of the formulation has to be kept in mind while formulating a compound as per the general pH requirement of the body of patients as well as that needed for maintaining preservatives in the compound. Preservatives used in the syrup can be many such as methyl parabens, propyl parabens, calcium sorbate, potassium sorbate, all benzoates and other such preservatives that work only in low pH. All of this requirement may be well achieved by certain companies that comply with GMP regulations. Even if there is a dearth of such a company, one may rely on a popular liquid manufacturing machine exporter that.